1H-pyrrolo[5,4-b]pyridin-3-amine - Names and Identifiers
Name | 3-AMINO-7-AZAINDOLE
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Synonyms | Amino-7-azaindole 3-AMINO-7-AZAINDOLE 1H-pyrrolo[5,4-b]pyridin-3-amine 1H-Pyrrolo[2,3-b]pyridin-3-amine 1H-Pyrrolo[2,3-b]pyridin-3-ylaMine 1H-Pyrrolo[2,3-b]pyridin-3-aMine HCl 1H-Pyrrolo[2,3-b]pyridin-3-amine(9CI) 1H-Pyrrolo[2,3-b]pyridin-3-ylaMine3-AMino-7-azaindole 3-Amino-7-azaindole (1H-Pyrrolo[2,3-b]pyridin-3-amine)
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CAS | 189882-31-3
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InChI | InChI=1/C7H7N3/c8-6-4-10-7-5(6)2-1-3-9-7/h1-4H,8H2,(H,9,10) |
1H-pyrrolo[5,4-b]pyridin-3-amine - Physico-chemical Properties
Molecular Formula | C7H7N3
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Molar Mass | 133.15 |
Density | 1.367 |
Melting Point | 194-196 °C |
Boling Point | 348.6±35.0 °C(Predicted) |
Flash Point | 165℃ |
Vapor Presure | 5.75E-06mmHg at 25°C |
pKa | 8.42±0.20(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.78 |
1H-pyrrolo[5,4-b]pyridin-3-amine - Risk and Safety
Safety Description | 24/25 - Avoid contact with skin and eyes.
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HS Code | 29339900 |
1H-pyrrolo[5,4-b]pyridin-3-amine - Introduction
3-AMINO-7-AZAINDOLE (also known as 3-amino-7h-pyrrole [2,3-d] pyrimidine) is a nitrogen-containing heterocyclic compound with the chemical formula C7H6N4. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 3-AMINO-7-AZAINDOLE is white or slightly yellow crystal.
-Melting point: Its melting point is about 240-244 degrees Celsius.
-Solubility: Soluble in organic solvents such as Alcohols, Ketones and esters, insoluble in water.
Use:
-Drug research: 3-AMINO-7-AZAINDOLE is an important intermediate compound, which is widely used as a starting material or intermediate for drug synthesis in the pharmaceutical field.
-Organic synthesis: It can be used to synthesize a variety of compounds with biological activity, such as pesticides, dyes and cosmetics.
Method:
There are many preparation methods for 3-AMINO-7-AZAINDOLE. The following is one of the commonly used methods:
-First, react 2,3-dichloropyridine with ammonia to produce 2-amino-3-chloropyridine.
-Then, 2-amino-3-chloropyridine is reacted with a tertiary amine (such as trimethylamine), and a cyclization reaction is carried out under appropriate reaction conditions to generate 3-AMINO-7-AZAINDOLE.
Safety Information:
- 3-AMINO-7-AZAINDOLE is generally considered to be a relatively safe compound under normal use conditions.
-However, as a chemical, it is still necessary to pay attention to compliance with safe operating regulations.
-Avoid contact with skin and wear protective gloves and goggles.
-Good ventilation should be maintained during operation.
-If ingested or inhaled, seek medical attention immediately.
Please note that this is only a brief introduction to 3-AMINO-7-AZAINDOLE. Please further confirm the relevant information in the specific application and follow the correct chemical laboratory operation specifications.
Last Update:2024-04-09 21:01:54